Surgical pathology is a foundation for accurate and cutting-edge diagnosis in the rapidly evolving and ever-expanding landscape of medicine, critically guiding clinical decisions and therapeutic strategies. This potentially innovative and transformative environment is best experienced in the domain of liver tumors – an organ in which one needs to “think out of the liver” as it is commonly involved by a complex spectrum of benign and malignant lesions of varied histogenesis that challenge and confound even the most experienced pathologists. The demand for precision, speed, and interdisciplinary collaboration has never been greater as the burden of hepatic malignancies continues to rise in tandem with global increase in risk factors such as ageing population with susceptibility for cancers, and metabolic dysfunction-associated steatotic liver disease.